Associate Professor at UFV. Head of the Molecular Oncology Group. Hospital 12 de Octubre, Pancreatic Cancer, 🧪🔬Epigenetics, Therapeutic targets, Python, Machine Learning, Statistics and Bioinformatics. 🖥️🧬
Victor Javier
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#PancreaticCancer induces B cell lineage plasticity via Pax5 inhibition to sustain immunosuppression 🧪 www.nature.com/articles/s41...
Matched pancreatic cancer liver metastatic model system reveals cancer cell-dependent organotropism and site-specific tumor microenvironment reflective of human disease www.biorxiv.org/content/10.6... #PancreaticCancer 🧪
JOSD1-mediated stabilization of SUFU controls pancreatic cancer progression www.nature.com/articles/s41... #PancreaticCancer 🧪
BioNeuralNet: A Graph Neural Network based Multi-Omics Network Data Analysis Tool 🧬🖥️🧪 academic.oup.com/bioinformati...
Victor Javier
TF-DWGNet: a directed weighted graph neural network with tensor fusion for multi-omics cancer subtype classification academic.oup.com/nargab/artic...
Immunomodulation of #PancreaticCancer via Inhibition of SUMOylation and the CD155/TIGIT Pathway 🧪 aacrjournals.org/mct/article/...
Restaging after neoadjuvant FOLFIRINOX for localized pancreatic cancer: a clinical calculator from the Trans-Atlantic Pancreatic Surgery consortium #PancreaticCancer 🧪 academic.oup.com/jnci/article...
Exosomal miR‐4644 Targets SPRY3 to Promote Proliferation and Invasion of #PancreaticCancer 🧪 onlinelibrary.wiley.com/doi/10.1002/...
Aberrant alternative splicing of purinergic receptor P2RX4 prevents sensitivity towards combinatorial treatment in colorectal and #PancreaticCancer 🧪 pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/...
Identification of Pancreatic Ductal Adenocarcinoma Extracellular Matrix Signatures from In-Depth Proteomic Profiling that Correlate with Lymphocyte Infiltration #PancreaticCancer 🧪 aacrjournals.org/cancerrescom...
Victor Javier
Victor Javier
Victor Javier
Cell Death Discovery - Pancreatic cancer induces B cell lineage plasticity via Pax5 inhibition to sustain immunosuppression
Abstract. Integration and analysis of multi-omics data provide valuable insights for improving cancer subtype classification. However, such data are inhere
Abstract. Pancreatic ductal adenocarcinoma (PDAC) is the deadliest major cancer and has a profoundly immunosuppressive tumor microenvironment (TME). Previous studies have shown that inhibition of the ...
Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4-expressing epithelial tumors to prevent paracrine resistance. Here, we ...
AbstractBackground. Restaging after neoadjuvant chemotherapy aims to assess treatment response, revise prognosis, and guide further management. This study
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Background
Tumor-derived exosomes (TDEs) can carry diverse genetic material that modulates pancreatic cancer (PC) proliferation and invasion. Despite this, the involvement of microRNAs (miRNAs) in T.....
AbstractThe extracellular matrix (ECM) is a complex assembly of proteins surrounding cells. It is a critical component of the tumor microenvironment (TME) that plays an active role in tumor progressio...
